METOLYZIN (Metolazone) is a thiazide-like diuretic indicated for the management of edema associated with heart failure, renal disorders, and hypertension. It works by inhibiting sodium reabsorption in the distal tubules, promoting effective fluid and sodium excretion. Metolazone is particularly useful in patients with reduced renal function and is often combined with loop diuretics for enhanced diuretic response. It supports effective fluid balance and improved cardiovascular outcomes in appropriate patients.